No, this is not a treatment option for Alzheimer's disease.
No, this is not a treatment option for Alzheimer's disease. This is a wildly exaggerated interpretation of a preclinical study demonstrating an already well-documented phenomenon. NSAIDs such as ibuprofen and mefenamic acid reduce neuroinflammation in transgenic mouse models of AD. The problem is that prospective trials of such drugs have repeatedly failed to treat or prevent progression of AD, so this phenomenon is of little clinical significance. There no news here, but news media are already hyping this story --- patients and their families will once again be given false hope by the headline.
Shame on you, University of Manchester media shill Jamie Brown.
http://www.eurekalert.org/pub_releases/2016-08/uom-tof080916.php
Shame on you, University of Manchester media shill Jamie Brown.
http://www.eurekalert.org/pub_releases/2016-08/uom-tof080916.php
It may work in transgenic mice but not in humans. It's a cruel hoax.
ReplyDeleteMari Christian results like this call into question whether we have the right preclinical models.
ReplyDeleteExactly Lev. I hate the way this kind of sloppy work makes it into the popular press as a "breakthough".
ReplyDeleteMari Christian I'm sure the work is fine. The problem is the press release and the motivation behind it.
ReplyDelete